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Hydrogen production by catalytic gasification of cellulose in supercritical water

GUAN Yu, PEI Aixia, GUO Liejin

《化学科学与工程前沿（英文）》 2008年 第2卷 第2期   页码 176-180 doi: 10.1007/s11705-008-0026-z

摘要： Cellulose, one of the important components of biomass, was gasified in supercritical water to produce hydrogen-rich gas in an autoclave which was operated batch-wise under high-pressure. KCO and Ca(OH) were selected as the catalysts (or promoters). The temperature was kept between 450°C and 500°C while pressure was maintained at 24–26 MPa. The reaction time was 20 min. Experimental results showed that the two catalysts had good catalytic effect and optimum amounts were observed for each catalyst. When 0.2 g KCO was added, the hydrogen yield could reach 9.456 molkg which was two times of the H amount produced without catalyst. When 1.6 g Ca(OH) was added, the H yield was 8.265 molkg which is lower than that obtained using KCO as catalyst but is still 1.7 times that achieved without catalyst. Comparing with the results obtained using KCO or Ca(OH) alone, the use of a combination of KCO and Ca(OH) could increase the H yield by up to 2.5 times that without catalyst and 25% and 45% more than that obtained using KCO and Ca(OH) alone, respectively. It was found that methane was the dominant product at relatively low temperature. When the temperature was increased, the methane reacts with water and is converted to hydrogen and carbon dioxide.

关键词： reaction     temperature     combination     catalytic effect     dominant product    

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Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition

null

《医学前沿（英文）》 2016年 第10卷 第3期   页码 311-319 doi: 10.1007/s11684-016-0460-0

摘要：

We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e., Tac-β3, Tac-β3D741, Tac-β3D747, Tac-β3D754, Tac-β3D759, and Tac-β3DNITY) consisting of the extracellular and transmembrane domains of human IL-2 receptor (Tac) and the human integrin β3 cytoplasmic domain were stably expressed in the 123 CHO cells harboring human glycoprotein Ib-IX and wild-type integrin αIIbβ3. The different cells were assayed for stable adhesion and spreading on immobilized fibrinogen, and for binding soluble fibrinogen representing outside-in and inside-out signaling events, respectively. The chimeric protein Tac-β3 inhibited, and Tac-β3DNITY partially attenuated stable adhesion and spreading. Tac-β3, Tac-β3D759, Tac-β3DNITY, and Tac-β3D754, but not Tac-β3D747 or Tac-β3D741, impaired the soluble fibrinogen binding. Results indicated that the bidirectional signaling was significantly inhibited by Tac-β3 and Tac-β3DNITY, albeit to a much lesser extent. Moreover, only inside-out signaling was impaired in the 123/Tac-β3D759 and 123/Tac-β3D754 cells in contrast to an intact bidirectional signaling in the 123/Tac-β3D747 and 123/Tac-β3D741 cells. In conclusion, the calpain cleavage of integrin β3 resulted in the regulatory effects on signaling by interrupting its interaction with cytoplasmic proteins rather than altering its conformation, and may thus regulate platelet function.

关键词： integrin β3     signal transduction     trans-dominant inhibition model    

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Investigation of polyhydroxyalkanoates (PHAs) biosynthesis from mixed culture enriched by valerate-dominant

Jiuxiao Hao, Xiujin Wang, Hui Wang

《环境科学与工程前沿（英文）》 2017年 第11卷 第1期 doi: 10.1007/s11783-017-0896-8

摘要： Valerate-hydrolysate enriched culture showed great ability to produce 3HV and 3H2MV. Valerate-hydrolysate enriched culture had more in the community. Mixed iso-/n-valerate was effective at balancing microbial growth and PHAs synthesis. Co-substrates of valerate and propionate raised the fraction of 3HV and 3H2MV. The production of polyhydroxyalkanoates (PHAs) with a high fraction of 3-hydroxyvalerate (3HV) and 3-hydroxy-2-methylvalerate (3H2MV) from mixed culture enriched by valerate-dominant hydrolysate was evaluated in this study. After long-term enrichment, the culture showed strong ability to synthesize 3HV and 3H2MV, even with acetate-dominant substrate. The ultilization of single or mixed iso-/n-valerate by the enriched culture showed that the mixture of iso-valerate and n-valerate was more efficient substrate than any single in terms of balancing microbial growth and PHAs synthesis. Besides, through comparing the kinetics and stoichiometry of the tests supplying valerate and propionate, the enriched culture with equivalent valerate and propionate (1:1 molar ratio) exhibited superior PHAs production performances to pure valerate or propionate, attaining more than 70 mol% of 3HV and 3H2MV. The above findings reveal that valerate-dominant hydrolysate is a kind of suitable substrate to enrich PHAs producing culture with great capability to synthesize 3HV and 3H2MV monomers, thus improving product properties than pure poly(3-hydroxybutyrate) (P3HB); also 3HV and 3H2MV production behaviors can be regulated by the type of odd-carbon VFAs in the substrate.

关键词： Polyhydroxyalkanoates (PHAs)     Valerate     Mixed culture     3-hydroxyvalerate (3HV)     Propionate    

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Heavy metal accumulation and phytostabilization potential of dominant plant species growing on manganese

YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu

《环境科学与工程前沿（英文）》 2014年 第8卷 第3期   页码 394-404 doi: 10.1007/s11783-013-0602-4

摘要： Screening plants that are hypertolerant to and excluders of certain heavy metals plays a fundamental role in a remediation strategy for metalliferous mine tailings. A field survey of terrestrial higher plants growing on Mn mine tailings at Huayuan, Hunan Province, China was conducted to identify candidate species for application in phytostabilization of the tailings in this region. In total, 51 species belonging to 21 families were recorded and the 12 dominant plants were investigated for their potential in phytostabilization of heavy metals. Eight plant species, , , , , , , , and accumulated much lower concentrations of heavy metals in shoots and roots than the associated soils and bioconcentration factors (BFs) for Cd, Mn, Pb and Zn were all<1, demonstrating a high tolerance to heavy metals and poor metals translocation ability. The field investigation also found that these species grew fast, accumulated biomass rapidly and developed a vegetation cover in a relatively short time. Therefore, they are good candidates for phytostabilization purposes and could be used as pioneer species in phytoremediation of Mn mine tailings in this region of South China.

关键词： Mn mine tailings     heavy metal accumulation     phytostabilization    

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Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

《化学科学与工程前沿（英文）》 2017年 第11卷 第4期   页码 516-520 doi: 10.1007/s11705-017-1658-7

摘要： The patient receives a pharmaceutical product, not a drug. The pharmaceutical products are formulated with a drug, an active ingredient to produce the maximum therapeutic effect after oral absorption. Therefore, it is the product we must optimize for the patients. In order to assure the safety and efficacy of pharmaceutical products, we need an predictive tool for oral product performance in patients. Currently, we are a surprisingly long way from accomplishing that objective. If the 20th century was the ‘age of the drug’, i.e., the ‘magic bullet’, the 21st century must become the ‘age of the guided missile’, i.e., the delivery system, including the form of the active pharmaceutical ingredient (API) (‘drug’). The physical form of the drug and the delivery system must be optimized to maximize the therapeutic benefits of pharmaceutical products for humans. Oral immediate release (IR) dosage forms cannot be optimal for all drugs or likely even any drugs (APIs). Still, the formulation of pharmaceutical products has to be optimized for patients. But how do we optimize oral delivery of drugs? It is usually through ‘trial and error’, in humans! We need a better way to optimize the oral dosage forms. We have suggested to select different dissolution methodologies for this optimization based on BCS Subclasses. In this article, we present the predicted drug dissolution profile of ketoconazole as a model drug from our laboratory utilizing a gastrointestinal simulator (GIS), which is an adaptation of the ASD system. GIS consists of three chambers representing stomach, duodenum, and jejunum, to create the human gastrointestinal tract-like environment and enable the control the gastric emptying rate. This dissolution system allows the monitoring of the drug dissolution phenomena and the observation of the supersaturation and the precipitation of pharmaceutical products, which is useful information to predict dissolution of pharmaceutical products. This system can provide the actual input needed to accurately predict the input into the systemic circulation required by many of the absorption prediction packages available today.

关键词： GIS     in vivo predictive dissolution     ketoconazole     BCS subclassification     supersaturation    

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Review of sentiment analysis: An emotional product development view

《工程管理前沿（英文）》   页码 592-609 doi: 10.1007/s42524-022-0227-z

摘要： Conveying consumers’ specific emotions in new products, referred to as emotional product development or emotional design, is strategically crucial for manufacturers. Given that sentiment analysis (SA) can extract and analyze people’s opinions, sentiments, attitudes, and perceptions regarding different products/services, SA-based emotional design may provide manufacturers with real-time, direct, and rapid decision support. Despite its considerable advancements and numerous survey and review articles, SA is seldom considered in emotional design. This study is among the first efforts to conduct a thorough review of SA from the view of emotional design. The comprehensive review of aspect-level SA reveals the following: 1) All studies focus on extracting product features by mixing technical product features and consumers’ emotional perceptions. Consequently, such studies cannot capture the relationships between technical and emotional attributes and thus cannot convey specific emotions to the new products. 2) Most studies use the English language in SA, but other languages have recently received more interest in SA. Furthermore, after conceptualizing emotion as Kansei and introducing emotional product development and Kansei Engineering, a review of the data-driven emotional design is then conducted. A few efforts start to study emotional design with the help of SA. However, these studies only focus on either analyzing consumers’ preferences on product features or extracting emotional opinions from online reviews, thus cannot realize data-driven emotional product development. Finally, some research opportunities are provided. This study opens a broad door to aspect-level SA and its integration with emotional product development.

关键词： sentiment analysis     emotion     product development     Kansei Engineering    

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Lean Product Development—Faster, Better … Cleaner?

Geert Letens

《工程管理前沿（英文）》 2015年 第2卷 第1期   页码 52-59 doi: 10.15302/J-FEM-2015007

摘要： To address this challenge, lean product development has emerged to become the leading improvement methodology for companies toward the creation of a competitive advantage on innovation and technology leadership. While lean product development has its origin in the best practice studies of Japanese car manufacturers such as Toyota, it has been further elaborated in defence and aerospace organizations over the last two decades, and recently empirical evidence has become available for successful introductions in sectors different from the traditionally-studied environments. The primary purpose of this work is to untangle the fuzziness that still surrounds lean product development and to ground the key aspects of lean product development based on insights from six studies published in a special issue of the on this topic. This demonstrates how better and faster product development can be achieved through the integration of lean principles with the best of more traditional new product development (NPD) practices, into a holistic system that can be characterised by value-focused and risk-based decision making, the socio-technical integration of people and process, improved project, pipeline and portfolio management, optimized knowledge management, and the creation of a learning organization. Unfortunately, while the increasing global competition offers the potential to improve the quality of life for many, the spirit of faster, better, and cheaper also threatens to endanger the future of our planet as a whole. As the majority of a product’s social and ecological impacts are committed in the design phase, it, therefore, seems imperative to investigate the integration of lean product development and eco-design principles. As a result, this work also explores the symbiosis of both approaches through the identification of tools and methods that can support the triple bottom-line goals for a sustainable future of life and business.

关键词： lean product development     sustainability engineering     responsible design    

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An energy consumption prediction approach of die casting machines driven by product parameters

《机械工程前沿（英文）》 2021年 第16卷 第4期   页码 868-886 doi: 10.1007/s11465-021-0656-0

摘要： Die casting machines, which are the core equipment of the machinery manufacturing industry, consume great amounts of energy. The energy consumption prediction of die casting machines can support energy consumption quota, process parameter energy-saving optimization, energy-saving design, and energy efficiency evaluation; thus, it is of great significance for Industry 4.0 and green manufacturing. Nevertheless, due to the uncertainty and complexity of the energy consumption in die casting machines, there is still a lack of an approach for energy consumption prediction that can provide support for process parameter optimization and product design taking energy efficiency into consideration. To fill this gap, this paper proposes an energy consumption prediction approach for die casting machines driven by product parameters. Firstly, the system boundary of energy consumption prediction is defined, and subsequently, based on the energy consumption characteristics analysis, a theoretical energy consumption model is established. Consequently, a systematic energy consumption prediction approach for die casting machines, involving product, die, equipment, and process parameters, is proposed. Finally, the feasibility and reliability of the proposed energy consumption prediction approach are verified with the help of three die casting machines and six types of products. The results show that the prediction accuracy of production time and energy consumption reached 91.64% and 85.55%, respectively. Overall, the proposed approach can be used for the energy consumption prediction of different die casting machines with different products.

关键词： die casting machine     energy consumption prediction     product parameters    

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A hybrid method for product low-end disruptive innovation

《机械工程前沿（英文）》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0690-6

摘要： Product innovation is often a process for improving existing products. Low-end disruptive innovation (LDI) enables a product to meet the most price-sensitive customers in the low-end market. The existing LDI methods are mainly based on unnecessary characteristics of disruptive innovations. Thus, they cannot easily identify and respond to the LDI design needs. This study proposes a hybrid method for the product LDI in two levels of the product design based on the summarized definition and essential characteristics of LDI. Feasible areas of the product LDI are determined using a hybrid relational function model to identify the maturity of dominant technologies. The technologies are identified through the technical search and evaluation of the feasible area for innovation to form an initial LDI scheme. Then, the product function is optimized using the trimming concept of theory of inventive problem solving based on the characteristics of LDI. The final LDI scheme is formed and evaluated based on the essential characteristics of the product LDI. The feasibility of the proposed method is verified in the design of a new dropping pill machine.

关键词： low-end disruptive innovation     product design     design improvement     theory of inventive problem solving     TRIZ     trimming    

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Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

《机械工程前沿（英文）》 2020年 第15卷 第1期   页码 12-23 doi: 10.1007/s11465-019-0555-9

摘要： The distributed parameterized intelligent product platform (DPIPP) contains many agents of a product minimum approximate autonomous subsystem (generalized module). These distributed agents communicate, coordinate, and cooperate using their knowledge and skills and eventually accomplish the design for mass customization in a loosely coupled environment. In this study, a new method of isomorphism analysis on generalized modules oriented to DPIPP is proposed. First, on the basis of the bill of material partition and generalized module mining, the parameters of the main characteristics are extracted to construct the main characteristic parameter matrix. Second, similarity calculation of generalized modules is realized by improving the clustering using representatives algorithm, and isomorphism model sets are obtained. Generalized modules with a similar structure are combined to complete the isomorphism analysis. The effectiveness of the proposed method is verified by taking high- and medium-pressure valve data as an example.

关键词： distributed parameterized intelligent product platform     generalized module     isomorphism analysis     product family    

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Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method

WANG Fenghao, JIANG Gedong, Lin John Zhang

《能源前沿（英文）》 2008年 第2卷 第3期   页码 243-248 doi: 10.1007/s11708-008-0049-7

摘要： A fluid-structure interaction model based on Surface Vorticity Method (SVM) was used to study flow-induced vibrations of tube bundles in medium space ratio. The flow-induced vibrations of four tubes in a rotated square and a staggered tube bundle in three-row and five-column arrangements were simulated in the high sub-critical Reynolds number () range. The results on fluid forces, tube responses and vorticity maps were presented. The vorticity maps of the four rotated-square tubes changed dramatically when the rigid tubes were replaced by the flexible tubes. From the vorticity maps and vibration responses of the staggered tube bundle of different structural parameters, it was found that with the decrease of tube natural frequency, the maximal vibration response moved from the third row to the first. The results also showed that when more flexible tubes are used, the flow pattern changed drastically and the fluid-structure interaction imposed a dominant impact on the flow.

关键词： dominant     sub-critical Reynolds     staggered     Vorticity     three-row    

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Highlights in agri-product quality and safety

Guanghong ZHOU

《农业科学与工程前沿（英文）》 2018年 第5卷 第3期   页码 289-290 doi: 10.15302/J-FASE-2018236

摘要：

关键词： valign=     top     class=     J_zhaiyao    

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Massively efficient filter for topology optimization based on the splitting of tensor product structure

《机械工程前沿（英文）》 2022年 第17卷 第4期 doi: 10.1007/s11465-022-0710-6

摘要： In this work, we put forward a massively efficient filter for topology optimization (TO) utilizing the splitting of tensor product structure. With the aid of splitting technique, the traditional weight matrices of B-splines and non-uniform rational B-spline implicit filters are decomposed equivalently into two or three submatrices, by which the sensitivity analysis is reformulated for the nodal design variables without altering the optimization process. Afterwards, an explicit sensitivity filter, which is decomposed by the splitting pipeline as that applied to implicit filter, is established in terms of the tensor product of the axial distances between adjacent element centroids, and the corresponding sensitivity analysis is derived for elemental design variables. According to the numerical results, the average updating time for the design variables is accelerated by two-order-of-magnitude for the decomposed filter compared with the traditional filter. In addition, the memory burden and computing time of the weight matrix are decreased by six- and three-order-of-magnitude for the decomposed filter. Therefore, the proposed filter is massively improved by the splitting of tensor product structure and delivers a much more efficient way of solving TO problems in the frameworks of isogeometric analysis and finite element analysis.

关键词： topology optimization     isogeometric analysis     finite element analysis     tensor product structure     sensitivity analysis    

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2019 highlights of the structural revision of natural product

Zongjia Chen, Mark A. Rizzacasa

《化学科学与工程前沿（英文）》 2021年 第15卷 第3期   页码 595-601 doi: 10.1007/s11705-020-1971-4

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General closed-form inverse kinematics for arbitrary three-joint subproblems based on the product of

《机械工程前沿（英文）》 2022年 第17卷 第2期 doi: 10.1007/s11465-022-0681-7

摘要： The inverse kinematics problems of robots are usually decomposed into several Paden–Kahan subproblems based on the product of exponential model. However, the simple combination of subproblems cannot solve all the inverse kinematics problems, and there is no common approach to solve arbitrary three-joint subproblems in an arbitrary postural relationship. The novel algebraic geometric (NAG) methods that obtain the general closed-form inverse kinematics for all types of three-joint subproblems are presented in this paper. The geometric and algebraic constraints are used as the conditions precedent to solve the inverse kinematics of three-joint subproblems. The NAG methods can be applied in the inverse kinematics of three-joint subproblems in an arbitrary postural relationship. The inverse kinematics simulations of all three-joint subproblems are implemented, and simulation results indicating that the inverse solutions are consistent with the given joint angles validate the general closed-form inverse kinematics. Huaque III minimally invasive surgical robot is used as the experimental platform for the simulation, and a master–slave tracking experiment is conducted to verify the NAG methods. The simulation result shows the inverse solutions and six sets given joint angles are consistent. Additionally, the mean and maximum of the master–slave tracking experiment for the closed-form solution are 0.1486 and 0.4777 mm, respectively, while the mean and maximum of the master–slave tracking experiment for the compensation method are 0.3188 and 0.6394 mm, respectively. The experiments results demonstrate that the closed-form solution is superior to the compensation method. The results verify the proposed general closed-form inverse kinematics based on the NAG methods.

关键词： inverse kinematics     Paden–Kahan subproblems     three-joint subproblems     product of exponential     closed-form solution    

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标题 作者 时间 类型 操作

Hydrogen production by catalytic gasification of cellulose in supercritical water

GUAN Yu, PEI Aixia, GUO Liejin

期刊论文

Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition

null

期刊论文

Investigation of polyhydroxyalkanoates (PHAs) biosynthesis from mixed culture enriched by valerate-dominant

Jiuxiao Hao, Xiujin Wang, Hui Wang

期刊论文

Heavy metal accumulation and phytostabilization potential of dominant plant species growing on manganese

YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu

期刊论文

Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

期刊论文

Review of sentiment analysis: An emotional product development view

期刊论文

Lean Product Development—Faster, Better … Cleaner?

Geert Letens

期刊论文

An energy consumption prediction approach of die casting machines driven by product parameters

期刊论文

A hybrid method for product low-end disruptive innovation

期刊论文

Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

期刊论文

Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method

WANG Fenghao, JIANG Gedong, Lin John Zhang

期刊论文

Highlights in agri-product quality and safety

Guanghong ZHOU

期刊论文

Massively efficient filter for topology optimization based on the splitting of tensor product structure

期刊论文

2019 highlights of the structural revision of natural product

Zongjia Chen, Mark A. Rizzacasa

期刊论文

General closed-form inverse kinematics for arbitrary three-joint subproblems based on the product of

期刊论文